| Gene Information | |
|---|---|
| Gene Name | CD180 |
| Organism | Homo sapiens (Human) |
| Gene Length | 661 |
| Protein Names | CD180 antigen (Lymphocyte antigen 64) (Radioprotective 105 kDa protein) (CD antigen CD180) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000134061 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q99467 |
| Gene Card | CD180 |
| Uniprot ID | Q99467 |
| Pfam | PF00560; PF18831; PF13855 |
| In ASD | no |
| Allosteric Prediction | no (-0.459262462) |
| Ortholog in Animals | Alpaca_ CD180 ( ortholog_one2one ) Dog_ CD180 ( ortholog_one2one ) GuineaPig_ CD180 ( ortholog_one2one ) Macaque_ CD180 ( ortholog_one2one ) Mouse_ Cd180 ( ortholog_one2one ) Pig_ CD180 ( ortholog_one2one ) Rat_ Cd180 ( ortholog_one2one ) Rabbit_ CD180 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RXFP1, TLR8, NRROS, TLR5, TSKU, TLR7, TLR10, RXFP2, TLR6, LRRC3B, IGFALS, TLR3, TLR2, TLR4, LRRC17, LRRC32, LRRC53, VASN, TLR1, LRRC3C, LRRC3, LRIT2 |
| Tissue | spleen |
| Tissue Specificity | Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.010990(Rat);0.200000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3B2D (X-ray 2.80A ) |
| DBSNP | rs5744463 rs16875312 rs2230520 rs5744525 rs56752081 rs2230523 rs2230524 |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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