| Gene Information | |
|---|---|
| Gene Name | LMTK2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1503 |
| Protein Names | Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000164715 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8IWU2 |
| Gene Card | LMTK2 |
| Uniprot ID | Q8IWU2 |
| Pfam | PF07714 |
| In ASD | no |
| Allosteric Prediction | no (-0.444472272) |
| Ortholog in Animals | Alpaca_ LMTK2 ( ortholog_one2one ) Alpaca_ LMTK2 ( ortholog_one2many ) Dog_ LMTK2 ( ortholog_one2one ) GuineaPig_ LMTK2 ( ortholog_one2one ) Macaque_ LMTK2 ( ortholog_one2one ) Mouse_ Lmtk2 ( ortholog_one2one ) Pig_ LMTK2 ( ortholog_one2one ) Rat_ Lmtk2 ( ortholog_one2one ) Rabbit_ LMTK2 ( ortholog_one2one ) |
| Ohnologs | AATK |
| Paralogs | EPHA7, NTRK1, EPHB3, ALK, FGFR3, EPHA2, EPHB1, EPHA3, INSR, PDGFRA, EGFR, CSF1R, ERBB3, KIT, NTRK3, DDR1, ERBB4, EPHA8, TEK, MUSK, MERTK, FGFR4, FLT3, EPHB6, FLT1, DDR2, EPHA6, NTRK2, IGF1R, INSRR, EPHB4, PDGFRB, ERBB2, KDR, EPHA5, FGFR2, TYRO3, MST1R, AXL, EPHB2, ROR1, ROR2, ROS1, EPHA10, EPHA4, RET, LTK, FLT4, TIE1, FGFR1, RYK, EPHA1, MET |
| Tissue | NA |
| Tissue Specificity | Mainly expressed in skeletal muscle, and weakly in brain and pancreas. {ECO:0000269|PubMed:12393858}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.00599(Rat);0.100000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3735252 rs147940573 rs34461195 rs34628253 rs56204700 rs11765552 rs56196840 rs34005293 rs55867257 rs3801295 rs35912712 rs56343792 rs45488394 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:23114966}; Multi-pass membrane protein {ECO:0000269|PubMed:23114966}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |