Gene Information
Gene NameLMLN
OrganismHomo sapiens (Human)
Gene Length655
Protein NamesLeishmanolysin-like peptidase (EC 3.4.24.-) (Invadolysin)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000185621 )
Evolutionary StageEukaryota
AlphaFoldDBQ96KR4
Gene CardLMLN
Uniprot IDQ96KR4
PfamPF01457
In ASDno
Allosteric Predictionno (-0.80379235)
Ortholog in AnimalsAlpaca_ LMLN ( ortholog_one2one )
Dog_ LMLN ( ortholog_one2one )
GuineaPig_ LMLN ( ortholog_one2one )
Macaque_ LMLN ( ortholog_one2one )
Mouse_ Lmln ( ortholog_one2one )
Pig_ LMLN ( ortholog_one2one )
Rat_ Lmln ( ortholog_one2one )
Rabbit_ LMLN ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in all cell lines analyzed. {ECO:0000269|PubMed:19706689}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs7373165 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:15557119}. Lipid droplet {ECO:0000269|PubMed:19706689}. Note=Found in ring-like structures resembling invadopodia. In migrating cells it relocalizes from internal structures to the leading edge of cells. {ECO:0000269|PubMed:19706689}.
Mouse PG classificationNA
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