| Gene Information | |
|---|---|
| Gene Name | POLA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 598 |
| Protein Names | DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit) |
| Target Name | dna polymerase alpha subunit b |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000014138 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q14181 |
| Gene Card | POLA2 |
| Uniprot ID | Q14181 |
| Pfam | PF04042; PF08418 |
| In ASD | no |
| Allosteric Prediction | yes (0.241514632) |
| Ortholog in Animals | Alpaca_ POLA2 ( ortholog_one2one ) Dog_ POLA2 ( ortholog_one2one ) GuineaPig_ POLA2 ( ortholog_one2one ) Macaque_ POLA2 ( ortholog_one2one ) Mouse_ Pola2 ( ortholog_one2one ) Pig_ POLA2 ( ortholog_one2one ) Rat_ Pola2 ( ortholog_one2one ) Rabbit_ POLA2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001899(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KEB (NMR - ) 4E2I (X-ray 5.00A ) 4Y97 (X-ray 2.51A ) 5EXR (X-ray 3.60A ) 7OPL (EM 4.12A ) 7U5C (EM 4.60A ) 8D0B (EM 3.43A ) 8D0K (EM 4.27A ) |
| DBSNP | rs487989 rs7123885 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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