| Gene Information | |
|---|---|
| Gene Name | LLN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 235 |
| Protein Names | Derlin-3 (Degradation in endoplasmic reticulum protein 3) (DERtrin-3) (Der1-like protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96Q80 |
| Gene Card | DERL3 |
| Uniprot ID | Q96Q80 |
| Pfam | PF04511 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Unlike DERL1 and DERL2, restricted to several tissues. Expressed at high levels in placenta, pancreas, spleen and small intestine. {ECO:0000269|PubMed:16449189}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);0.120000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3177243 rs1128127 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:16449189}; Multi-pass membrane protein {ECO:0000269|PubMed:16449189}. |
| Mouse PG classification | NA |
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