| Gene Information | |
|---|---|
| Gene Name | LIR5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 448 |
| Protein Names | Leukocyte immunoglobulin-like receptor subfamily B member 4 (B4) (CD85 antigen-like family member K) (Immunoglobulin-like transcript 3) (ILT-3) (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Monocyte inhibitory receptor HM18) (CD antigen CD85k) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8NHJ6 |
| Gene Card | LILRB4 |
| Uniprot ID | Q8NHJ6 |
| Pfam | PF00047; PF13895 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected on monocytes, macrophages, dendritic cells, natural killer cells and B-cells (at protein level). Expressed in the lung. {ECO:0000269|PubMed:19833736, ECO:0000269|PubMed:30333625, ECO:0000269|PubMed:9151699, ECO:0000269|PubMed:9278324, ECO:0000269|PubMed:9548455}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 3P2T (X-ray 1.70A ) 6K7O (X-ray 3.00A ) |
| DBSNP | rs28366008 rs11540761 rs11540762 rs731170 rs11574575 rs11574576 rs2764337 rs11574589 rs1048801 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:19833736, ECO:0000269|PubMed:9151699}; Single-pass type I membrane protein {ECO:0000269|PubMed:9151699}. Note=Ligand binding leads to internalization and translocation to an antigen-processing compartment. {ECO:0000269|PubMed:9151699}. |
| Mouse PG classification | NA |
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