| Gene Information | |
|---|---|
| Gene Name | LIPI |
| Organism | Homo sapiens (Human) |
| Gene Length | 460 |
| Protein Names | Lipase member I (LIPI) (EC 3.1.1.-) (Cancer/testis antigen 17) (CT17) (LPD lipase) (Membrane-associated phosphatidic acid-selective phospholipase A1-beta) (mPA-PLA1 beta) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000188992 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6XZB0 |
| Gene Card | LIPI |
| Uniprot ID | Q6XZB0 |
| Pfam | PF00151 |
| In ASD | no |
| Allosteric Prediction | no (-0.9914443) |
| Ortholog in Animals | Alpaca_ LIPI ( ortholog_one2one ) GuineaPig_ LIPI ( ortholog_one2one ) Macaque_ LIPI ( ortholog_one2one ) Mouse_ Lipi ( ortholog_one2one ) Pig_ LIPI ( ortholog_one2one ) Rat_ Lipi ( ortholog_one2one ) Rabbit_ LIPI ( ortholog_one2one ) |
| Ohnologs | LIPH |
| Paralogs | PNLIP, PLA1A, PNLIPRP3, LIPC, PNLIPRP2, LIPH, PNLIPRP1, LIPG, LPL |
| Tissue | NA |
| Tissue Specificity | Expressed in testis. Expressed exclusively at the connecting piece of the sperm. {ECO:0000269|PubMed:12719377, ECO:0000269|PubMed:12963729}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11909217 rs74369337 rs2822432 rs7278737 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000269|PubMed:12963729}. Secreted {ECO:0000269|PubMed:12963729}. Note=May associate with lipid draft. {ECO:0000269|PubMed:12963729}.; [Isoform 2]: Cell membrane {ECO:0000269|PubMed:12963729}. Secreted {ECO:0000269|PubMed:12963729}. Note=May associate with lipid draft. {ECO:0000269|PubMed:12963729}. |
| Mouse PG classification | HPG |
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