| Gene Information | |
|---|---|
| Gene Name | LIPH |
| Organism | Homo sapiens (Human) |
| Gene Length | 451 |
| Protein Names | Lipase member H (LIPH) (EC 3.1.1.-) (LPD lipase-related protein) (Membrane-associated phosphatidic acid-selective phospholipase A1-alpha) (mPA-PLA1 alpha) (Phospholipase A1 member B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000163898 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8WWY8 |
| Gene Card | LIPH |
| Uniprot ID | Q8WWY8 |
| Pfam | PF00151 |
| In ASD | no |
| Allosteric Prediction | yes (0.109599214) |
| Ortholog in Animals | Alpaca_ LIPH ( ortholog_one2one ) Dog_ LIPH ( ortholog_one2one ) GuineaPig_ LIPH ( ortholog_one2one ) Macaque_ LIPH ( ortholog_one2one ) Mouse_ Liph ( ortholog_one2one ) Pig_ LIPH ( ortholog_one2one ) Rat_ AABR07034648.1 ( ortholog_one2one ) Rabbit_ LIPH ( ortholog_one2one ) |
| Ohnologs | LIPI |
| Paralogs | PNLIP, PLA1A, PNLIPRP3, LIPI, LIPC, PNLIPRP2, PNLIPRP1, LIPG, LPL |
| Tissue | esophagus.mucosa, minor.salivary.gland, stomach, transverse.colon |
| Tissue Specificity | Present in intestine (at protein level). Expressed in colon, prostate, kidney, pancreas, ovary, testis, intestine, lung and pancreas. Expressed at lower level in brain, spleen and heart. In hair, it is prominently expressed in hair follicles, including the stem cell-rich bulge region. {ECO:0000269|PubMed:12063250, ECO:0000269|PubMed:12213196, ECO:0000269|PubMed:12719377, ECO:0000269|PubMed:17095700}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs267607219 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:12963729}. Cell membrane {ECO:0000269|PubMed:12063250, ECO:0000269|PubMed:12963729}; Peripheral membrane protein. |
| Mouse PG classification | HPG |
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