| Gene Information | |
|---|---|
| Gene Name | LIPC |
| Organism | Homo sapiens (Human) |
| Gene Length | 499 |
| Protein Names | Hepatic triacylglycerol lipase (HL) (Hepatic lipase) (EC 3.1.1.3) (Lipase member C) (Lysophospholipase) (EC 3.1.1.5) (Phospholipase A1) (EC 3.1.1.32) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000166035 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P11150 |
| Gene Card | LIPC |
| Uniprot ID | P11150 |
| Pfam | PF00151; PF01477 |
| In ASD | no |
| Allosteric Prediction | yes (0.236262243) |
| Ortholog in Animals | Alpaca_ LIPC ( ortholog_one2one ) Dog_ LIPC ( ortholog_one2one ) GuineaPig_ LIPC ( ortholog_one2one ) Macaque_ LIPC ( ortholog_one2one ) Mouse_ Lipc ( ortholog_one2one ) Pig_ LIPC ( ortholog_one2one ) Rat_ Lipc ( ortholog_one2one ) Rabbit_ LIPC ( ortholog_one2one ) |
| Ohnologs | LIPG, LPL |
| Paralogs | PNLIP, PLA1A, PNLIPRP3, LIPI, PNLIPRP2, LIPH, PNLIPRP1, LIPG, LPL |
| Tissue | liver |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6078 rs6083 rs121912502 rs145811475 rs3829462 rs113298164 rs142036980 rs6079 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:2828141}. |
| Mouse PG classification | LPG |
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