| Gene Information | |
|---|---|
| Gene Name | LIN7C |
| Organism | Homo sapiens (Human) |
| Gene Length | 197 |
| Protein Names | Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000148943 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9NUP9 |
| Gene Card | LIN7C |
| Uniprot ID | Q9NUP9 |
| Pfam | PF02828; PF00595 |
| In ASD | no |
| Allosteric Prediction | no (-0.805632005) |
| Ortholog in Animals | Alpaca_ LIN7C ( ortholog_one2one ) Dog_ LIN7C ( ortholog_one2many ) GuineaPig_ LIN7C ( ortholog_one2one ) Macaque_ LIN7C ( ortholog_one2one ) Mouse_ Lin7c ( ortholog_one2one ) Pig_ LIN7C ( ortholog_one2one ) Rat_ Lin7c ( ortholog_one2one ) Rabbit_ LIN7C ( ortholog_one2one ) |
| Ohnologs | LIN7B, LIN7A |
| Paralogs | LIN7B, LIN7A, PDZD11 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.013588(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3LRA (X-ray 2.95A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12967566}; Peripheral membrane protein {ECO:0000269|PubMed:12967566}. Basolateral cell membrane {ECO:0000269|PubMed:12967566}; Peripheral membrane protein {ECO:0000269|PubMed:12967566}. Cell junction {ECO:0000250}. Postsynaptic density membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Note=Mainly basolateral in renal epithelial cells. {ECO:0000250}. |
| Mouse PG classification | NA |
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