| Gene Information | |
|---|---|
| Gene Name | TOMM70 |
| Organism | Homo sapiens (Human) |
| Gene Length | 608 |
| Protein Names | Mitochondrial import receptor subunit TOM70 (Mitochondrial precursor proteins import receptor) (Translocase of outer membrane 70 kDa subunit) (Translocase of outer mitochondrial membrane protein 70) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000154174 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | O94826 |
| Gene Card | TOMM70 |
| Uniprot ID | O94826 |
| Pfam | PF00515; PF13181 |
| In ASD | no |
| Allosteric Prediction | no (-0.772180366) |
| Ortholog in Animals | Alpaca_ TOMM70 ( ortholog_one2one ) Dog_ TOMM70 ( ortholog_one2one ) GuineaPig_ TOMM70 ( ortholog_one2one ) Macaque_ TOMM70 ( ortholog_one2one ) Mouse_ Tomm70a ( ortholog_one2one ) Pig_ TOMM70 ( ortholog_one2one ) Rat_ Tomm70 ( ortholog_one2one ) Rabbit_ TOMM70 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TTC1, TTC32, SUGT1, UNC45A, TTC4, TOMM34, SPAG1, SGTB, UNC45B, DNAAF4, TTC31, ST13, TTC12, STIP1, SPATA16, SGTA, RPAP3, STUB1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004067(Rat);0.046154(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 7DHG (X-ray 2.20A ) 7KDT (EM 3.05A ) |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion outer membrane {ECO:0000269|PubMed:20628368, ECO:0000269|PubMed:25609812, ECO:0000269|PubMed:33723040}; Single-pass membrane protein {ECO:0000255}.; Note=(Microbial infection) During parasite T.gondii-mediated infection, enriched at the interface between the host mitochondria and the parasitopharous vacuole. {ECO:0000269|PubMed:33723040}. |
| Mouse PG classification | NA |
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