Gene Information
Gene NameASPA
OrganismHomo sapiens (Human)
Gene Length313
Protein NamesAspartoacylase (EC 3.5.1.15) (Aminoacylase-2) (ACY-2)
Target Nameaspartoacylase
Target TypeNA
Gene Age680 ( ENSG00000108381 )
Evolutionary StageEuk+Bac
AlphaFoldDBP45381
Gene CardASPA
Uniprot IDP45381
PfamPF04952
In ASDno
Allosteric Predictionno (-0.192719409)
Ortholog in AnimalsAlpaca_ ASPA ( ortholog_one2one )
Dog_ ASPA ( ortholog_one2one )
GuineaPig_ ASPA ( ortholog_one2one )
Macaque_ ASPA ( ortholog_one2one )
Mouse_ Aspa ( ortholog_one2one )
Pig_ ASPA ( ortholog_one2one )
Rat_ Aspa ( ortholog_one2one )
Rabbit_ ASPA ( ortholog_one2one )
OhnologsACY3
ParalogsACY3
TissueNA
Tissue SpecificityBrain white matter, skeletal muscle, kidney, adrenal glands, lung and liver.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2I3C  (X-ray  2.80A  2O4H  (X-ray  2.70A  2O53  (X-ray  2.70A  2Q51  (X-ray  2.80A  4MRI  (X-ray  2.80A  4MXU  (X-ray  2.60A  4NFR  (X-ray  3.00A  4TNU  (X-ray  2.90A 
DBSNP rs769653717  rs104894551  rs766328537  rs1555538144  rs1555538148  rs1555538151  rs776777887  rs1446467099  rs1057521115  rs773049803  rs777936704  rs104894548  rs937670540  rs770706390  rs144321760  rs1014551540  rs786204572  rs1555539857  rs104894550  rs1057516995  rs104894552  rs761064915  rs1555541310  rs750505963  rs28940279  rs1414684396  rs774323189  rs28940574  rs376854191 
Subcellular location [CC]Cytoplasm. Nucleus {ECO:0000250}.
Mouse PG classificationNA
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