| Gene Information | |
|---|---|
| Gene Name | GLG1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1179 |
| Protein Names | Golgi apparatus protein 1 (CFR-1) (Cysteine-rich fibroblast growth factor receptor) (E-selectin ligand 1) (ESL-1) (Golgi sialoglycoprotein MG-160) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000090863 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q92896 |
| Gene Card | GLG1 |
| Uniprot ID | Q92896 |
| Pfam | PF00839 |
| In ASD | no |
| Allosteric Prediction | yes (0.024665038) |
| Ortholog in Animals | Alpaca_ GLG1 ( ortholog_one2one ) GuineaPig_ GLG1 ( ortholog_one2one ) Macaque_ GLG1 ( ortholog_one2one ) Mouse_ Glg1 ( ortholog_one2one ) Pig_ GLG1 ( ortholog_one2one ) Rat_ Glg1 ( ortholog_one2one ) Rabbit_ GLG1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Highest levels in pancreas, skeletal muscle, placenta, heart, testis and ovary. Also found in the kidney, liver, lung and brain. {ECO:0000269|PubMed:9182700}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000269|PubMed:2355176}; Single-pass type I membrane protein {ECO:0000255}. Golgi outpost {ECO:0000250|UniProtKB:Q62638}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000250|UniProtKB:Q62638}. Note=Golgi medial cisternae. Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation. {ECO:0000250|UniProtKB:Q62638}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |