Gene Information
Gene NameLIME
OrganismHomo sapiens (Human)
Gene Length295
Protein NamesLck-interacting transmembrane adapter 1 (Lck-interacting membrane protein) (Lck-interacting molecule)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9H400
Gene CardLIME1
Uniprot IDQ9H400
PfamPF15332
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in peripheral blood lymphocytes, lymphoid tissues, and liver. Present in T-cells and plasma cells, and in various hematopoietic cell lines (at protein level). {ECO:0000269|PubMed:14610044, ECO:0000269|PubMed:14610046, ECO:0000269|PubMed:16160011}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs1151625 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:14610044, ECO:0000269|PubMed:14610046};
Single-pass type III membrane protein {ECO:0000269|PubMed:14610044, ECO:0000269|PubMed:14610046}. Note=Present in lipid rafts. Recruited to the immunological synapse upon conjugation of T-cell with antigen-presenting cell.
Mouse PG classificationNA
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