| Gene Information | |
|---|---|
| Gene Name | GRF2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1077 |
| Protein Names | Rap guanine nucleotide exchange factor 1 (CRK SH3-binding GNRP) (Guanine nucleotide-releasing factor 2) (Protein C3G) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q13905 |
| Gene Card | RAPGEF1 |
| Uniprot ID | Q13905 |
| Pfam | PF00617; PF00618 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed in adult and fetus. Expression is high in adult skeletal muscle and placenta and in fetal brain and heart. Low levels of expression in adult and fetal liver. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5L23 (X-ray 1.77A ) |
| DBSNP | NA |
| Subcellular location [CC] | Early endosome {ECO:0000269|PubMed:17724123}. |
| Mouse PG classification | NA |
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