| Gene Information | |
|---|---|
| Gene Name | LILRA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 489 |
| Protein Names | Leukocyte immunoglobulin-like receptor subfamily A member 1 (CD85 antigen-like family member I) (Leukocyte immunoglobulin-like receptor 6) (LIR-6) (CD antigen CD85i) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000104974 ) 3 ( ENSG00000274935 ) 3 ( ENSG00000275525 ) 3 ( ENSG00000277398 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O75019 |
| Gene Card | LILRA1 |
| Uniprot ID | O75019 |
| Pfam | PF00047; PF13895 |
| In ASD | no |
| Allosteric Prediction | no (-0.811702859) |
| Ortholog in Animals | Alpaca_ LILRB1 ( ortholog_one2many ) Mouse_ Pira1 ( ortholog_many2many ) Mouse_ Lilra6 ( ortholog_many2many ) Mouse_ Pira12 ( ortholog_many2many ) Mouse_ Pira2 ( ortholog_many2many ) Mouse_ Pira13 ( ortholog_many2many ) Mouse_ Lilra5 ( ortholog_many2many ) Mouse_ Pirb ( ortholog_many2many ) Rat_ Lilrb2 ( ortholog_many2many ) Rat_ Lilra5 ( ortholog_many2many ) Rat_ Lilrc2 ( ortholog_many2many ) Rat_ Lilrb1 ( ortholog_many2many ) Rat_ Lilrb3 ( ortholog_many2many ) Rat_ Lilrb3a ( ortholog_many2many ) Rat_ Lilrb3l ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | LILRB1, LILRB2, LILRA2, LILRB5, LILRA4, LILRA6, LILRA5, LILRB4, LILRB3, NCR1, KIR2DL3, KIR3DL3, KIR3DL2, KIR3DL1, KIR2DS4, KIR2DL4, FCAR, KIR2DL1, GP6, IGSF1, OSCAR, TARM1, VSTM1, LAIR2, A1BG |
| Tissue | appendix, spleen, lymph.node, whole.blood |
| Tissue Specificity | Detected in monocytes and B-cells. {ECO:0000269|PubMed:9548455}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1974982 rs10417589 rs373854 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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