| Gene Information | |
|---|---|
| Gene Name | LIF |
| Organism | Homo sapiens (Human) |
| Gene Length | 202 |
| Protein Names | Leukemia inhibitory factor (LIF) (Differentiation-stimulating factor) (D factor) (Melanoma-derived LPL inhibitor) (MLPLI) (Emfilermin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000128342 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P15018 |
| Gene Card | LIF |
| Uniprot ID | P15018 |
| Pfam | PF01291 |
| In ASD | no |
| Allosteric Prediction | no (-0.583191366) |
| Ortholog in Animals | Alpaca_ LIF ( ortholog_one2one ) Dog_ LIF ( ortholog_one2one ) GuineaPig_ LIF ( ortholog_one2one ) Macaque_ LIF ( ortholog_one2one ) Mouse_ Lif ( ortholog_one2one ) Pig_ LIF ( ortholog_one2one ) Rat_ Lif ( ortholog_one2one ) Rabbit_ LIF ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | tricuspid.valve |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.001000(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1EMR (X-ray 3.50A ) 1PVH (X-ray 2.50A ) 2Q7N (X-ray 4.00A ) 7N0A (X-ray 3.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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