| Gene Information | |
|---|---|
| Gene Name | LIC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 351 |
| Protein Names | Cytoplasmic dynein 2 light intermediate chain 1 (Dynein 2 light intermediate chain) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8TCX1 |
| Gene Card | DYNC2LI1 |
| Uniprot ID | Q8TCX1 |
| Pfam | PF05783 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in bone, brain, kidney, and cartilage (PubMed:26077881, PubMed:26130459). Lower expression in heart, liver, lung, placenta and thymus (PubMed:26077881). {ECO:0000269|PubMed:26077881, ECO:0000269|PubMed:26130459}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.185714(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6RLB (EM 4.50A ) 6SC2 (EM 3.90A ) |
| DBSNP | rs2288709 rs17854966 rs201948500 rs886037860 rs11556157 |
| Subcellular location [CC] | Golgi apparatus {ECO:0000269|PubMed:11907264}. Cytoplasm {ECO:0000269|PubMed:26130459}. Cell projection, cilium {ECO:0000269|PubMed:26130459, ECO:0000269|PubMed:29742051}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:26130459, ECO:0000269|PubMed:29742051}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q8K0T2}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:26130459}. Note=Localizes to the apical cytoplasm. {ECO:0000250|UniProtKB:Q8K0T2}. |
| Mouse PG classification | NA |
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