Gene Information | |
---|---|
Gene Name | LHPP |
Organism | Homo sapiens (Human) |
Gene Length | 270 |
Protein Names | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (hLHPP) (EC 3.1.3.-) (EC 3.6.1.1) |
Target Name | NA |
Target Type | NA |
Gene Age | 645 ( ENSG00000107902 ) |
Evolutionary Stage | Euk+Bac |
AlphaFoldDB | Q9H008 |
Gene Card | LHPP |
Uniprot ID | Q9H008 |
Pfam | PF13344 |
In ASD | no |
Allosteric Prediction | no (-0.313030605) |
Ortholog in Animals | Alpaca_ LHPP ( ortholog_one2one ) Dog_ LHPP ( ortholog_one2one ) GuineaPig_ LHPP ( ortholog_one2one ) Macaque_ LHPP ( ortholog_one2one ) Mouse_ Lhpp ( ortholog_one2one ) Pig_ LHPP ( ortholog_one2one ) Rat_ Lhpp ( ortholog_one2one ) Rabbit_ LHPP ( ortholog_one2one ) |
Ohnologs | NA |
Paralogs | PDXP, PGP, HDHD2 |
Tissue | NA |
Tissue Specificity | Expressed in brain, and at lower levels in liver and kidney. Detected in thyroid (at protein level). Expressed in liver, kidney and moderately in brain. {ECO:0000269|PubMed:12801912, ECO:0000269|PubMed:16430861}. |
Pharmacological Animal Models | NA |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | 2X4D (X-ray 1.92A ) |
DBSNP | rs6597801 |
Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16430861}. Nucleus {ECO:0000269|PubMed:16430861}. |
Mouse PG classification | NA |
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