| Gene Information | |
|---|---|
| Gene Name | SERPINA6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 405 |
| Protein Names | Corticosteroid-binding globulin (CBG) (Serpin A6) (Transcortin) |
| Target Name | corticosteroid-binding globulin |
| Target Type | Successful target |
| Gene Age | 168 ( ENSG00000170099 ) 3 ( ENSG00000277405 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P08185 |
| Gene Card | SERPINA6 |
| Uniprot ID | P08185 |
| Pfam | PF00079 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000197194) |
| Ortholog in Animals | Alpaca_ SERPINA6 ( ortholog_one2one ) Dog_ SERPINA6 ( ortholog_one2one ) GuineaPig_ SERPINA6 ( ortholog_one2one ) Macaque_ SERPINA6 ( ortholog_one2one ) Mouse_ Serpina6 ( ortholog_one2one ) Pig_ SERPINA6 ( ortholog_one2one ) Rat_ Serpina6 ( ortholog_one2one ) Rabbit_ SERPINA6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SERPING1, SERPINB7, SERPINF1, SERPINI1, AGT, SERPIND1, SERPINA7, SERPINB8, SERPINI2, HMSD, SERPINB6, SERPINC1, SERPINB1, SERPINA10, SERPINH1, SERPINB13, SERPINA3, SERPINA5, SERPINA9, SERPINA12, SERPINE1, SERPINF2, SERPINA4, SERPINB11, SERPINB5, SERPINB12, SERPINB9, SERPINE3, SERPINB4, SERPINB3, SERPINE2, SERPINA1, SERPINA2, SERPINB10, SERPINA11, SERPINB2 |
| Tissue | liver |
| Tissue Specificity | Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 2VDX (X-ray 1.84A ) 2VDY (X-ray 2.30A ) 4BB2 (X-ray 2.48A ) 4C41 (X-ray 1.80A ) 4C49 (X-ray 2.70A ) |
| DBSNP | rs113418909 rs2228541 rs28929488 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | LPG |
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