| Gene Information | |
|---|---|
| Gene Name | LGI4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 537 |
| Protein Names | Leucine-rich repeat LGI family member 4 (LGI1-like protein 3) (Leucine-rich glioma-inactivated protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000153902 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q8N135 |
| Gene Card | LGI4 |
| Uniprot ID | Q8N135 |
| Pfam | PF03736; PF13855 |
| In ASD | no |
| Allosteric Prediction | no (-1.350633851) |
| Ortholog in Animals | Alpaca_ LGI4 ( ortholog_one2one ) Dog_ LGI4 ( ortholog_one2one ) GuineaPig_ LGI4 ( ortholog_one2one ) Macaque_ LGI4 ( ortholog_one2one ) Mouse_ Lgi4 ( ortholog_one2one ) Pig_ LGI4 ( ortholog_one2one ) Rat_ Lgi4 ( ortholog_one2one ) Rabbit_ LGI4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LRG1, CPN2, LRRTM2, LRRC52, LRIT3, LRRC24, ELFN2, LRIG3, LGR6, LGR5, CHAD, CHADL, LRIT1, TRIL, ELFN1, LGR4, LGI2, LGI1, LRIG2, LRRC26, LRIG1, LGI3 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest expression in brain. {ECO:0000269|PubMed:12023020}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs755500591 rs1064797094 |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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