| Gene Information | |
|---|---|
| Gene Name | ST6GAL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 406 |
| Protein Names | Beta-galactoside alpha-2,6-sialyltransferase 1 (Alpha 2,6-ST 1) (EC 2.4.3.1) (B-cell antigen CD75) (CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1) (ST6Gal I) (ST6GalI) (Sialyltransferase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000073849 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P15907 |
| Gene Card | ST6GAL1 |
| Uniprot ID | P15907 |
| Pfam | PF00777 |
| In ASD | no |
| Allosteric Prediction | no (-0.763490587) |
| Ortholog in Animals | Alpaca_ ST6GAL1 ( ortholog_one2one ) Dog_ ST6GAL1 ( ortholog_one2one ) GuineaPig_ ST6GAL1 ( ortholog_one2one ) Macaque_ ST6GAL1 ( ortholog_one2one ) Mouse_ St6gal1 ( ortholog_one2one ) Pig_ ST6GAL1 ( ortholog_one2one ) Rat_ St6gal1 ( ortholog_one2one ) Rabbit_ ST6GAL1 ( ortholog_one2one ) |
| Ohnologs | ST6GAL2 |
| Paralogs | ST6GALNAC5, C20orf173, ST3GAL4, ST3GAL3, ST3GAL2, ST6GALNAC4, ST6GALNAC3, ST6GALNAC6, ST6GALNAC2, ST3GAL5, ST3GAL6, ST6GAL2, ST6GALNAC1, ST3GAL1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4JS1 (X-ray 2.09A ) 4JS2 (X-ray 2.30A ) 6QVS (X-ray 1.60A ) 6QVT (X-ray 1.70A ) |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:20378551}; Single-pass type II membrane protein {ECO:0000305}. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid. |
| Mouse PG classification | NA |
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