| Gene Information | |
|---|---|
| Gene Name | URI1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 535 |
| Protein Names | Unconventional prefoldin RPB5 interactor 1 (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000105176 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O94763 |
| Gene Card | URI1 |
| Uniprot ID | O94763 |
| Pfam | PF02996 |
| In ASD | no |
| Allosteric Prediction | no (-0.097240086) |
| Ortholog in Animals | Alpaca_ URI1 ( ortholog_one2one ) Alpaca_ URI1 ( ortholog_one2many ) Dog_ URI1 ( ortholog_one2one ) GuineaPig_ URI1 ( ortholog_one2one ) Macaque_ URI1 ( ortholog_one2one ) Mouse_ Uri1 ( ortholog_one2one ) Pig_ URI1 ( ortholog_one2one ) Rat_ Uri1 ( ortholog_one2one ) Rabbit_ URI1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Expressed in ovarian cancers (at protein level). Expressed strongly in skeletal muscle. Expressed weakly in brain, heart, pancreas and in prostate epithelial cells. {ECO:0000269|PubMed:21397856, ECO:0000269|PubMed:21730289, ECO:0000269|PubMed:9819440, ECO:0000269|PubMed:9878255}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002553(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs189187 |
| Subcellular location [CC] | Nucleus. Cytoplasm. Mitochondrion. Cell projection, dendrite {ECO:0000250}. Note=Colocalizes with PFDN2, PFDN4, PPP1CC, RPS6KB1 and STAP1 at mitochondrion. |
| Mouse PG classification | NA |
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