| Gene Information | |
|---|---|
| Gene Name | LETM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 739 |
| Protein Names | Mitochondrial proton/calcium exchanger protein (Leucine zipper-EF-hand-containing transmembrane protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000168924 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O95202 |
| Gene Card | LETM1 |
| Uniprot ID | O95202 |
| Pfam | PF07766 |
| In ASD | no |
| Allosteric Prediction | no (-0.579366301) |
| Ortholog in Animals | Alpaca_ LETM1 ( ortholog_one2one ) Dog_ LETM1 ( ortholog_one2one ) GuineaPig_ LETM1 ( ortholog_one2one ) Macaque_ LETM1 ( ortholog_one2one ) Mouse_ Letm1 ( ortholog_one2one ) Pig_ LETM1 ( ortholog_one2one ) Rat_ Letm1 ( ortholog_one2one ) |
| Ohnologs | LETM2 |
| Paralogs | LETM2, LETMD1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:14706454, ECO:0000269|PubMed:15138253, ECO:0000269|PubMed:18628306, ECO:0000269|PubMed:19797662}; Single-pass membrane protein {ECO:0000269|PubMed:14706454, ECO:0000269|PubMed:15138253, ECO:0000269|PubMed:18628306}. |
| Mouse PG classification | NA |
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