| Gene Information | |
|---|---|
| Gene Name | LEM3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 615 |
| Protein Names | Ankyrin repeat and LEM domain-containing protein 1 (EC 3.1.-.-) (Ankyrin repeat domain-containing protein 41) (LEM-domain containing protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8NAG6 |
| Gene Card | ANKLE1 |
| Uniprot ID | Q8NAG6 |
| Pfam | PF12796; PF03020 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expression is predominant in adult bone marrow. {ECO:0000269|PubMed:22399800}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs8100241 rs1864116 rs8108174 rs59119993 rs2363956 rs891017 rs11086065 rs34112069 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:22399800, ECO:0000269|PubMed:27245214}. Nucleus {ECO:0000269|PubMed:22399800, ECO:0000269|PubMed:27245214}. Note=At the steady state, localizes predominantly in the cytoplasm. {ECO:0000269|PubMed:22399800, ECO:0000269|PubMed:27245214}. |
| Mouse PG classification | NA |
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