| Gene Information | |
|---|---|
| Gene Name | LEFTY1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 366 |
| Protein Names | Left-right determination factor 1 (Left-right determination factor B) (Protein lefty-1) (Protein lefty-B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000243709 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O75610 |
| Gene Card | LEFTY1 |
| Uniprot ID | O75610 |
| Pfam | PF00019; PF00688 |
| In ASD | no |
| Allosteric Prediction | no (-1.141705395) |
| Ortholog in Animals | Alpaca_ LEFTY1 ( ortholog_one2one ) Mouse_ Lefty1 ( ortholog_many2many ) Mouse_ Lefty2 ( ortholog_many2many ) Rat_ Lefty2 ( ortholog_many2many ) Rat_ Lefty1 ( ortholog_many2many ) |
| Ohnologs | NA |
| Paralogs | LEFTY2, BMP3, MSTN, INHBC, GDF15, BMP6, INHBA, GDF6, TGFB3, BMP2, BMP10, TGFB1, INHA, GDF9, GDF11, BMP5, BMP7, INHBB, GDF5, GDF1, GDF2, BMP4, GDF3, INHBE, GDF7, GDF10, BMP15, TGFB2, BMP8A, BMP8B, NODAL |
| Tissue | colon, pancreas, rectum, sigmoid.colon, transverse.colon |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35273824 rs145431393 rs191758097 rs360057 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
| click here to return to the previous page | |