Gene Information
Gene NameLEC1
OrganismHomo sapiens (Human)
Gene Length1459
Protein NamesAdhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin homolog 1) (Latrophilin-2) (Lectomedin-1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBO95490
Gene CardADGRL2
Uniprot IDO95490
PfamPF00002; PF16489; PF02140; PF01825; PF02793; PF02354; PF02191
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed very widely in all normal tissues tested. Expression is variable in tumor cell lines, apparently elevated in some lines and absent or markedly reduced in others. {ECO:0000269|PubMed:10030676}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.002240(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Membrane {ECO:0000255};
Multi-pass membrane protein {ECO:0000255}.
Mouse PG classificationNA
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