| Gene Information | |
|---|---|
| Gene Name | PEPD |
| Organism | Homo sapiens (Human) |
| Gene Length | 493 |
| Protein Names | Xaa-Pro dipeptidase (X-Pro dipeptidase) (EC 3.4.13.9) (Imidodipeptidase) (Peptidase D) (Proline dipeptidase) (Prolidase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000124299 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P12955 |
| Gene Card | PEPD |
| Uniprot ID | P12955 |
| Pfam | PF05195; PF00557 |
| In ASD | no |
| Allosteric Prediction | yes (0.201563658) |
| Ortholog in Animals | Alpaca_ PEPD ( ortholog_one2one ) Dog_ PEPD ( ortholog_one2one ) GuineaPig_ PEPD ( ortholog_one2one ) Macaque_ PEPD ( ortholog_one2one ) Mouse_ Pepd ( ortholog_one2one ) Pig_ PEPD ( ortholog_one2one ) Rat_ AABR07002969.1 ( ortholog_one2one ) Rabbit_ PEPD ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | XPNPEP1, METAP1D, PA2G4, XPNPEP2, METAP2, METAP1, XPNPEP3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2IW2 (X-ray 1.82A ) 2OKN (X-ray 2.45A ) 5M4G (X-ray 1.48A ) 5M4J (X-ray 1.55A ) 5M4L (X-ray 1.49A ) 5M4Q (X-ray 1.73A ) 5MBY (X-ray 1.55A ) 5MBZ (X-ray 1.50A ) 5MC0 (X-ray 1.56A ) 5MC1 (X-ray 1.43A ) 5MC2 (X-ray 1.70A ) 5MC3 (X-ray 1.52A ) 5MC4 (X-ray 1.80A ) 5MC5 (X-ray 1.90A ) 6H2P (X-ray 1.48A ) 6H2Q (X-ray 1.78A ) 6QSB (X-ray 1.99A ) 6QSC (X-ray 1.57A ) 6SRE (X-ray 1.39A ) 6SRF (X-ray 1.85A ) 6SRG (X-ray 2.56A ) |
| DBSNP | rs121917722 rs121917721 rs121917723 rs2230062 rs17570 rs121917724 rs757386104 |
| Subcellular location [CC] | NA |
| Mouse PG classification | LPG |
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