| Gene Information | |
|---|---|
| Gene Name | IGFBP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 259 |
| Protein Names | Insulin-like growth factor-binding protein 1 (IBP-1) (IGF-binding protein 1) (IGFBP-1) (Placental protein 12) (PP12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000146678 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P08833 |
| Gene Card | IGFBP1 |
| Uniprot ID | P08833 |
| Pfam | PF00219; PF00086 |
| In ASD | no |
| Allosteric Prediction | yes (0.334760126) |
| Ortholog in Animals | Alpaca_ IGFBP1 ( ortholog_one2one ) GuineaPig_ IGFBP1 ( ortholog_one2one ) Macaque_ IGFBP1 ( ortholog_one2one ) Mouse_ Igfbp1 ( ortholog_one2one ) Pig_ IGFBP1 ( ortholog_one2one ) Rat_ Igfbp1 ( ortholog_one2one ) Rabbit_ IGFBP1 ( ortholog_one2one ) |
| Ohnologs | IGFBP4, IGFBP6, IGFBP2, IGFBP5 |
| Paralogs | IGFBP6, IGFBP3, IGFBP2, IGFBP5, IGFBP4 |
| Tissue | liver, placenta |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.133333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1ZT3 (X-ray 1.80A ) 1ZT5 (X-ray 1.82A ) 2DSQ (X-ray 2.80A ) |
| DBSNP | rs41258845 rs1065782 rs4619 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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