| Gene Information | |
|---|---|
| Gene Name | LDB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 411 |
| Protein Names | LIM domain-binding protein 1 (LDB-1) (Carboxyl-terminal LIM domain-binding protein 2) (CLIM-2) (LIM domain-binding factor CLIM2) (hLdb1) (Nuclear LIM interactor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000198728 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86U70 |
| Gene Card | LDB1 |
| Uniprot ID | Q86U70 |
| Pfam | PF17916; PF01803 |
| In ASD | no |
| Allosteric Prediction | no (-1.26063525) |
| Ortholog in Animals | Alpaca_ LDB1 ( ortholog_one2one ) Dog_ LDB1 ( ortholog_one2one ) GuineaPig_ LDB1 ( ortholog_one2one ) Macaque_ LDB1 ( ortholog_one2one ) Mouse_ Ldb1 ( ortholog_one2one ) Pig_ LDB1 ( ortholog_one2one ) Rat_ Ldb1 ( ortholog_one2one ) Rabbit_ LDB1 ( ortholog_one2one ) |
| Ohnologs | LDB2 |
| Paralogs | LDB2 |
| Tissue | NA |
| Tissue Specificity | Expressed in a wide range of adult tissues including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:16815859}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2XJY (X-ray 2.40A ) 2XJZ (X-ray 2.80A ) 2YPA (X-ray 2.80A ) 6TYD (X-ray 2.80A ) 7OB5 (X-ray 1.80A ) 7OB8 (X-ray 1.80A ) |
| DBSNP | rs990101456 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:P70662}. Note=Colocalizes with SLK at leading edges. {ECO:0000250|UniProtKB:P70662}. |
| Mouse PG classification | NA |
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