| Gene Information | |
|---|---|
| Gene Name | LDAH |
| Organism | Homo sapiens (Human) |
| Gene Length | 325 |
| Protein Names | Lipid droplet-associated hydrolase (EC 3.1.1.-) (Lipid droplet-associated serine hydrolase) (hLDAH) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000118961 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H6V9 |
| Gene Card | LDAH |
| Uniprot ID | Q9H6V9 |
| Pfam | PF10230 |
| In ASD | no |
| Allosteric Prediction | no (-0.540376007) |
| Ortholog in Animals | Alpaca_ LDAH ( ortholog_one2one ) Dog_ LDAH ( ortholog_one2one ) GuineaPig_ LDAH ( ortholog_one2one ) Macaque_ LDAH ( ortholog_one2one ) Mouse_ Ldah ( ortholog_one2one ) Pig_ LDAH ( ortholog_one2one ) Rat_ Ldah ( ortholog_one2one ) Rabbit_ LDAH ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Present in macrophage-rich areas in atherosclerotic lesionsv(at protein level). {ECO:0000269|PubMed:24357060}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Lipid droplet {ECO:0000269|PubMed:17135363}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8BVA5}. Note=Localizes to the endoplasmic reticulum in absence of lipid droplets and translocates to lipid droplets upon lipid storage induction. {ECO:0000250|UniProtKB:Q8BVA5}. |
| Mouse PG classification | NA |
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