Gene Information
Gene NameLCTL
OrganismHomo sapiens (Human)
Gene Length567
Protein NamesLactase-like protein (Klotho/lactase-phlorizin hydrolase-related protein)
Target Namelactase-like protein
Target TypeNA
Gene Age544 ( ENSG00000188501 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ6UWM7
Gene CardLCTL
Uniprot IDQ6UWM7
PfamPF00232
In ASDno
Allosteric Predictionno (-0.748499539)
Ortholog in AnimalsAlpaca_ LCTL ( ortholog_one2one )
Dog_ LCTL ( ortholog_one2one )
GuineaPig_ LCTL ( ortholog_one2one )
Macaque_ LCTL ( ortholog_one2one )
Mouse_ Lctl ( ortholog_one2one )
Pig_ LCTL ( ortholog_one2one )
Rat_ Lctl ( ortholog_one2one )
Rabbit_ LCTL ( ortholog_one2one )
OhnologsKL
ParalogsLCT, GBA3, KLB, KL
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs7179073  rs1030986 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000250};
Single-pass membrane protein {ECO:0000250}.
Mouse PG classificationNA
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