Gene Information
Gene NameMBOAT7
OrganismHomo sapiens (Human)
Gene Length472
Protein NamesLysophospholipid acyltransferase 7 (LPLAT 7) (EC 2.3.1.-) (1-acylglycerophosphatidylinositol O-acyltransferase) (Bladder and breast carcinoma-overexpressed gene 1 protein) (Leukocyte receptor cluster member 4) (Lysophosphatidylinositol acyltransferase) (LPIAT) (Lyso-PI acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 7) (O-acyltransferase domain-containing protein 7) (h-mboa-7)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000125505 )
3 ( ENSG00000273592 )
3 ( ENSG00000274194 )
3 ( ENSG00000275118 )
3 ( ENSG00000276935 )
3 ( ENSG00000277025 )
3 ( ENSG00000277733 )
3 ( ENSG00000277923 )
3 ( ENSG00000278322 )
3 ( ENSG00000278519 )
Evolutionary StageEumetazoa
AlphaFoldDBQ96N66
Gene CardMBOAT7
Uniprot IDQ96N66
PfamPF03062
In ASDno
Allosteric Predictionno (-0.517932676)
Ortholog in AnimalsAlpaca_ MBOAT7 ( ortholog_one2many )
Dog_ MBOAT7 ( ortholog_one2one )
GuineaPig_ MBOAT7 ( ortholog_one2one )
Macaque_ MBOAT7 ( ortholog_one2one )
Mouse_ Mboat7 ( ortholog_one2one )
Pig_ MBOAT7 ( ortholog_one2one )
Rat_ Mboat7 ( ortholog_one2one )
OhnologsNA
ParalogsLPCAT3, PORCN, MBOAT1, MBOAT4, MBOAT2
TissueNA
Tissue SpecificityOverexpressed in metastatic breast and bladder carcinomas relative to normal breast epithelium and urothelium. {ECO:0000269|PubMed:18772128}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17855385  rs35909464 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000269|PubMed:23510452, ECO:0000269|PubMed:30959108};
Multi-pass membrane protein {ECO:0000305|PubMed:30959108}. Note=Localized in specific membrane structures termed mitochondria-associated membranes (MAMs) which connect the endoplasmic reticulum (ER) and the mitochondria. {ECO:0000269|PubMed:23510452}.
Mouse PG classificationNA
click here to return to the previous page