| Gene Information | |
|---|---|
| Gene Name | LCB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 562 |
| Protein Names | Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O15270 |
| Gene Card | SPTLC2 |
| Uniprot ID | O15270 |
| Pfam | PF00155 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:17023427}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6M4N (EM 3.80A ) 6M4O (EM 3.40A ) 7CQI (EM 3.20A ) 7CQK (EM 3.30A ) 7K0I (EM 3.30A ) 7K0J (EM 3.10A ) 7K0K (EM 2.60A ) 7K0L (EM 3.40A ) 7K0M (EM 2.90A ) 7K0N (EM 3.10A ) 7K0O (EM 3.10A ) 7K0P (EM 3.10A ) 7K0Q (EM 3.30A ) |
| DBSNP | rs864621998 rs775437084 rs267607090 rs267607089 rs267607091 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P97363}; Single-pass membrane protein {ECO:0000250|UniProtKB:P97363}. |
| Mouse PG classification | NA |
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