| Gene Information | |
|---|---|
| Gene Name | LBP |
| Organism | Homo sapiens (Human) |
| Gene Length | 481 |
| Protein Names | Lipopolysaccharide-binding protein (LBP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000129988 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P18428 |
| Gene Card | LBP |
| Uniprot ID | P18428 |
| Pfam | PF01273; PF02886 |
| In ASD | no |
| Allosteric Prediction | no (-0.215393987) |
| Ortholog in Animals | Alpaca_ LBP ( ortholog_one2one ) Dog_ LBP ( ortholog_one2one ) GuineaPig_ LBP ( ortholog_one2one ) Macaque_ LBP ( ortholog_one2one ) Mouse_ Lbp ( ortholog_one2one ) Pig_ LBP ( ortholog_one2one ) Rat_ Lbp ( ortholog_one2one ) Rabbit_ LBP ( ortholog_one2one ) |
| Ohnologs | BPIFC |
| Paralogs | BPI, BPIFC, PLTP, CETP, BPIFB2, BPIFB6, BPIFB4, BPIFB3, BPIFA2, BPIFA1, BPIFA3, BPIFB1 |
| Tissue | liver |
| Tissue Specificity | Detected in blood serum (at protein level). {ECO:0000269|PubMed:2402637, ECO:0000269|PubMed:24120359}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2232580 rs2232583 rs2232585 rs36015492 rs2232586 rs5744204 rs2232601 rs2232607 rs2232608 rs2232613 rs5744212 rs2232615 rs2232618 rs2232619 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:2402637, ECO:0000269|PubMed:24120359, ECO:0000269|PubMed:7517398}. Cytoplasmic granule membrane {ECO:0000250|UniProtKB:P17213}. Note=Membrane-associated in polymorphonuclear Leukocytes (PMN) granules. {ECO:0000250|UniProtKB:P17213}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |