| Gene Information | |
|---|---|
| Gene Name | LASP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 261 |
| Protein Names | LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000002834 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q14847 |
| Gene Card | LASP1 |
| Uniprot ID | Q14847 |
| Pfam | PF00412; PF00880; PF14604 |
| In ASD | no |
| Allosteric Prediction | no (-0.141699487) |
| Ortholog in Animals | Alpaca_ LASP1 ( ortholog_one2one ) Dog_ LASP1 ( ortholog_one2one ) GuineaPig_ LASP1 ( ortholog_one2one ) Macaque_ LASP1 ( ortholog_one2one ) Mouse_ Lasp1 ( ortholog_one2one ) Pig_ LASP1 ( ortholog_one2one ) Rat_ Lasp1 ( ortholog_one2one ) Rabbit_ LASP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NEB, KY, NRAP, NEBL |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3I35 (X-ray 1.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cell cortex {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Associated with the F-actin rich cortical cytoskeleton. {ECO:0000250}. |
| Mouse PG classification | NA |
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