| Gene Information | |
|---|---|
| Gene Name | LAS1L |
| Organism | Homo sapiens (Human) |
| Gene Length | 734 |
| Protein Names | Ribosomal biogenesis protein LAS1L (Protein LAS1 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000001497 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y4W2 |
| Gene Card | LAS1L |
| Uniprot ID | Q9Y4W2 |
| Pfam | PF04031 |
| In ASD | no |
| Allosteric Prediction | no (-1.200348802) |
| Ortholog in Animals | Alpaca_ LAS1L ( ortholog_one2one ) Dog_ LAS1L ( ortholog_one2one ) GuineaPig_ LAS1L ( ortholog_one2one ) Macaque_ LAS1L ( ortholog_one2one ) Mouse_ Las1l ( ortholog_one2one ) Pig_ LAS1L ( ortholog_one2one ) Rat_ Las1l ( ortholog_one2one ) Rabbit_ LAS1L ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.21(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1371889606 rs1057518699 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:20647540}. Nucleus, nucleoplasm {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions (By similarity). Localizes mainly to the granular component, the region implicated in the later steps of rRNA processing and subunit assembly and export. {ECO:0000250}. |
| Mouse PG classification | NA |
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