| Gene Information | |
|---|---|
| Gene Name | LAPTM5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 262 |
| Protein Names | Lysosomal-associated transmembrane protein 5 (Lysosomal-associated multitransmembrane protein 5) (Retinoic acid-inducible E3 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000162511 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q13571 |
| Gene Card | LAPTM5 |
| Uniprot ID | Q13571 |
| Pfam | PF03821 |
| In ASD | no |
| Allosteric Prediction | no (-0.975442782) |
| Ortholog in Animals | Alpaca_ LAPTM5 ( ortholog_one2one ) Dog_ LAPTM5 ( ortholog_one2one ) GuineaPig_ LAPTM5 ( ortholog_one2one ) Macaque_ LAPTM5 ( ortholog_one2one ) Mouse_ Laptm5 ( ortholog_one2one ) Pig_ LAPTM5 ( ortholog_one2one ) Rat_ Laptm5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LAPTM4A, LAPTM4B |
| Tissue | NA |
| Tissue Specificity | Preferentially expressed in adult hematopoietic tissues. High levels in lymphoid and myeloid tissues. Highly expressed in peripheral blood leukocytes, thymus, spleen and lung, followed by placenta, liver and kidney. {ECO:0000269|PubMed:8661146}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35351292 |
| Subcellular location [CC] | Lysosome membrane {ECO:0000269|PubMed:8661146}; Multi-pass membrane protein {ECO:0000269|PubMed:8661146}. |
| Mouse PG classification | NA |
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