| Gene Information | |
|---|---|
| Gene Name | LAP |
| Organism | Homo sapiens (Human) |
| Gene Length | 1338 |
| Protein Names | Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9HC77 |
| Gene Card | CENPJ |
| Uniprot ID | Q9HC77 |
| Pfam | PF07202 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.010102(Chimpanzee);0.001000(Mouse);0.011620(Rat);0.048000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5EIB (X-ray 2.10A ) 5ITZ (X-ray 2.20A ) 7Q1E (X-ray 2.70A ) 7Z0F (X-ray 2.40A ) 7Z0G (X-ray 3.49A ) |
| DBSNP | rs35498994 rs17081389 rs7336216 rs9511510 rs34177811 rs17402892 rs121434311 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:11003675, ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:20531387}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:17681131, ECO:0000269|PubMed:20531387, ECO:0000269|PubMed:22020124}. Note=Localized within the center of microtubule asters (PubMed:11003675). During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles (PubMed:17681131). {ECO:0000269|PubMed:11003675, ECO:0000269|PubMed:17681131}. |
| Mouse PG classification | NA |
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