Gene Information
Gene NameCNOT8
OrganismHomo sapiens (Human)
Gene Length292
Protein NamesCCR4-NOT transcription complex subunit 8 (EC 3.1.13.4) (CAF1-like protein) (CALIFp) (CAF2) (CCR4-associated factor 8) (Caf1b)
Target NameNA
Target TypeNA
Gene Age>4290 ( ENSG00000155508 )
Evolutionary StageEukaryota
AlphaFoldDBQ9UFF9
Gene CardCNOT8
Uniprot IDQ9UFF9
PfamPF04857
In ASDno
Allosteric Predictionyes (0.137357243)
Ortholog in AnimalsAlpaca_ CNOT8 ( ortholog_one2one )
Dog_ CNOT8 ( ortholog_one2one )
GuineaPig_ CNOT8 ( ortholog_one2one )
Macaque_ CNOT8 ( ortholog_one2one )
Mouse_ Cnot8 ( ortholog_one2one )
Pig_ CNOT8 ( ortholog_one2one )
Rat_ Cnot8 ( ortholog_one2one )
Rabbit_ CNOT8 ( ortholog_one2one )
OhnologsCNOT7
ParalogsCNOT7
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.005431(Rat);0.034028(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs1139980 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:12771185}. Nucleus {ECO:0000269|PubMed:12771185}.
Mouse PG classificationNA
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