Gene Information
Gene NameLALP70
OrganismHomo sapiens (Human)
Gene Length616
Protein NamesEctonucleoside triphosphate diphosphohydrolase 4 (NTPDase 4) (EC 3.6.1.15) (EC 3.6.1.6) (Golgi UDPase) (Lysosomal apyrase-like protein of 70 kDa) (Uridine-diphosphatase) (UDPase) (EC 3.6.1.42)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9Y227
Gene CardENTPD4
Uniprot IDQ9Y227
PfamPF01150
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitous. Highest expression in testis and lowest in bladder. {ECO:0000269|PubMed:10393803, ECO:0000269|PubMed:9556635}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 6WG5  (X-ray  2.60A 
DBSNP rs549468877  rs2272641 
Subcellular location [CC][Isoform 1]: Cytoplasmic vesicle, autophagosome membrane {ECO:0000269|PubMed:10393803};
Multi-pass membrane protein {ECO:0000305}. Lysosome membrane {ECO:0000269|PubMed:10393803};
Multi-pass membrane protein.;
[Isoform 2]: Golgi apparatus membrane {ECO:0000269|PubMed:9556635};
Multi-pass membrane protein {ECO:0000255}.
Mouse PG classificationNA
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