| Gene Information | |
|---|---|
| Gene Name | LAGE3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 143 |
| Protein Names | EKC/KEOPS complex subunit LAGE3 (L antigen family member 3) (Protein ESO-3) (Protein ITBA2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000196976 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q14657 |
| Gene Card | LAGE3 |
| Uniprot ID | Q14657 |
| Pfam | PF09341 |
| In ASD | no |
| Allosteric Prediction | no (-0.965009008) |
| Ortholog in Animals | Alpaca_ LAGE3 ( ortholog_one2one ) Mouse_ Lage3 ( ortholog_one2one ) Rabbit_ LAGE3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CTAG1A, CTAG2, CTAG1B |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12384295, ECO:0000269|PubMed:8786131}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.054545(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6GWJ (X-ray 1.95A ) |
| DBSNP | rs1557211306 rs1557211209 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:28805828}. Nucleus {ECO:0000269|PubMed:22912744, ECO:0000269|PubMed:27903914, ECO:0000269|PubMed:28805828}. |
| Mouse PG classification | NA |
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