| Gene Information | |
|---|---|
| Gene Name | L3MBT |
| Organism | Homo sapiens (Human) |
| Gene Length | 840 |
| Protein Names | Lethal(3)malignant brain tumor-like protein 1 (H-l(3)mbt) (H-l(3)mbt protein) (L(3)mbt-like) (L(3)mbt protein homolog) (L3MBTL1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9Y468 |
| Gene Card | L3MBTL1 |
| Uniprot ID | Q9Y468 |
| Pfam | PF02820; PF01530 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expression is reduced in colorectal cancer cell line SW480 and promyelocytic leukemia cell line HL-60. {ECO:0000269|PubMed:10445843}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1OYX (X-ray 1.85A ) 1OZ2 (X-ray 1.55A ) 1OZ3 (X-ray 1.85A ) 2PQW (X-ray 2.00A ) 2RHI (X-ray 1.66A ) 2RHU (X-ray 1.90A ) 2RHX (X-ray 2.10A ) 2RHY (X-ray 1.90A ) 2RHZ (X-ray 2.20A ) 2RI2 (X-ray 2.20A ) 2RI3 (X-ray 2.00A ) 2RI5 (X-ray 2.00A ) 2RJC (X-ray 2.00A ) 2RJD (X-ray 1.65A ) 2RJE (X-ray 1.86A ) 2RJF (X-ray 2.05A ) 3OQ5 (X-ray 2.50A ) 3P8H (X-ray 2.55A ) 3UWN (X-ray 2.15A ) 6BYB (X-ray 1.74A ) |
| DBSNP | rs17857202 rs6017104 rs6030948 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:10445843}. Note=Excluded from the nucleolus. Does not colocalizes with the PcG protein BMI1, suggesting that these two proteins do not belong to the same complex. |
| Mouse PG classification | NA |
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