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Gene Information
Gene Name
L16
Organism
Homo sapiens (Human)
Gene Length
1390
Protein Names
ATPase family AAA domain-containing protein 2 (EC 3.6.1.-) (AAA nuclear coregulator cancer-associated protein) (ANCCA)
Target Name
NA
Target Type
NA
Gene Age
NA
Evolutionary Stage
NA
AlphaFoldDB
Q6PL18
Gene Card
ATAD2
Uniprot ID
Q6PL18
Pfam
PF00004; PF17862; PF00439
In ASD
no
Allosteric Prediction
NA
Ortholog in Animals
NA
Ohnologs
NA
Paralogs
NA
Tissue
NA
Tissue Specificity
Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors. {ECO:0000269|PubMed:15721472, ECO:0000269|PubMed:17076897, ECO:0000269|PubMed:17660802}.
Pharmacological Animal Models
0.018801(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB
3DAI
(X-ray
1.95A
)
4QSP
(X-ray
1.60A
)
4QSQ
(X-ray
1.80A
)
4QSR
(X-ray
2.00A
)
4QSS
(X-ray
2.00A
)
4QST
(X-ray
2.05A
)
4QSU
(X-ray
1.90A
)
4QSV
(X-ray
1.90A
)
4QSW
(X-ray
1.80A
)
4QSX
(X-ray
1.93A
)
4QUT
(X-ray
1.70A
)
4QUU
(X-ray
1.80A
)
4TT2
(X-ray
2.50A
)
4TT4
(X-ray
2.70A
)
4TT6
(X-ray
2.00A
)
4TTE
(X-ray
1.80A
)
4TU4
(X-ray
1.73A
)
4TU6
(X-ray
2.27A
)
4TYL
(X-ray
1.85A
)
4TZ2
(X-ray
1.70A
)
4TZ8
(X-ray
2.15A
)
5A5N
(X-ray
1.95A
)
5A5O
(X-ray
2.04A
)
5A5P
(X-ray
2.03A
)
5A5Q
(X-ray
1.97A
)
5A5R
(X-ray
2.01A
)
5A81
(X-ray
2.03A
)
5A82
(X-ray
1.86A
)
5A83
(X-ray
2.09A
)
5EPB
(X-ray
1.50A
)
5F36
(X-ray
1.50A
)
5F3A
(X-ray
1.60A
)
5LJ0
(X-ray
1.82A
)
5QXI
(X-ray
1.64A
)
5QXJ
(X-ray
1.46A
)
5QXK
(X-ray
1.72A
)
5QXL
(X-ray
1.57A
)
5QXM
(X-ray
1.50A
)
5QXN
(X-ray
1.41A
)
5QXO
(X-ray
1.47A
)
5QXP
(X-ray
1.41A
)
5QXQ
(X-ray
1.55A
)
5QXR
(X-ray
1.66A
)
5QXS
(X-ray
1.62A
)
5QXT
(X-ray
1.55A
)
5QXU
(X-ray
1.65A
)
5QXV
(X-ray
1.74A
)
5QXW
(X-ray
1.78A
)
5QXX
(X-ray
1.58A
)
5QXY
(X-ray
1.54A
)
5QXZ
(X-ray
1.64A
)
5QY0
(X-ray
1.89A
)
5R4E
(X-ray
1.83A
)
5R4F
(X-ray
1.44A
)
5R4V
(X-ray
1.29A
)
5R4W
(X-ray
1.47A
)
5R4X
(X-ray
1.40A
)
5R4Y
(X-ray
1.84A
)
5R4Z
(X-ray
1.46A
)
6CPS
(X-ray
1.93A
)
6EPJ
(X-ray
1.65A
)
6EPR
(X-ray
2.05A
)
6EPS
(X-ray
2.08A
)
6EPT
(X-ray
1.65A
)
6EPU
(X-ray
1.80A
)
6EPV
(X-ray
1.79A
)
6EPW
(X-ray
1.92A
)
6EPX
(X-ray
1.84A
)
6HDN
(X-ray
1.90A
)
6HDO
(X-ray
2.61A
)
6HI3
(X-ray
2.40A
)
6HI4
(X-ray
1.69A
)
6HI5
(X-ray
1.59A
)
6HI6
(X-ray
1.64A
)
6HI7
(X-ray
1.74A
)
6HI8
(X-ray
1.90A
)
6HIA
(X-ray
1.90A
)
6HIB
(X-ray
2.03A
)
6HIC
(X-ray
1.77A
)
6HID
(X-ray
1.77A
)
6HIE
(X-ray
2.05A
)
6S55
(X-ray
2.09A
)
6S56
(X-ray
2.01A
)
6S57
(X-ray
1.82A
)
6YB4
(X-ray
1.85A
)
7M98
(X-ray
1.60A
)
7Q6T
(X-ray
2.05A
)
7Q6U
(X-ray
1.95A
)
7Q6V
(X-ray
1.96A
)
7Q6W
(X-ray
1.96A
)
DBSNP
rs3758122
Subcellular location [CC]
Nucleus {ECO:0000269|PubMed:17998543}.
Mouse PG classification
NA
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