| Gene Information | |
|---|---|
| Gene Name | L13 |
| Organism | Homo sapiens (Human) |
| Gene Length | 432 |
| Protein Names | E3 ubiquitin-protein ligase RNF135 (EC 2.3.2.27) (RIG-I E3 ubiquitin ligase) (REUL) (RING finger protein 135) (RING finger protein leading to RIG-I activation) (Riplet) (RING-type E3 ubiquitin transferase RNF135) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8IUD6 |
| Gene Card | RNF135 |
| Uniprot ID | Q8IUD6 |
| Pfam | PF00622 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in skeletal muscle, spleen, kidney, placenta, prostate, stomach, thyroid and tongue. Also weakly expressed in heart, thymus, liver and lung. {ECO:0000269|PubMed:19017631}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7JL1 (EM 3.90A ) 7JL3 (EM 4.20A ) |
| DBSNP | rs7225888 rs7211440 rs111902263 rs121918162 rs61749868 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19484123, ECO:0000269|PubMed:23950712}. Cytoplasm, Stress granule {ECO:0000269|PubMed:23950712}. |
| Mouse PG classification | NA |
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