| Gene Information | |
|---|---|
| Gene Name | AFF2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1311 |
| Protein Names | AF4/FMR2 family member 2 (Protein FMR-2) (FMR2P) (Protein Ox19) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000155966 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P51816 |
| Gene Card | AFF2 |
| Uniprot ID | P51816 |
| Pfam | PF18876; PF18875 |
| In ASD | no |
| Allosteric Prediction | no (-0.745525945) |
| Ortholog in Animals | Alpaca_ AFF2 ( ortholog_one2one ) Dog_ AFF2 ( ortholog_one2one ) GuineaPig_ AFF2 ( ortholog_one2one ) Macaque_ AFF2 ( ortholog_one2one ) Mouse_ Aff2 ( ortholog_one2one ) Pig_ AFF2 ( ortholog_one2one ) Rat_ Aff2 ( ortholog_one2one ) Rabbit_ AFF2 ( ortholog_one2one ) |
| Ohnologs | AFF1 |
| Paralogs | AFF3, AFF4, AFF1 |
| Tissue | bone.marrow, lymph.node, placenta |
| Tissue Specificity | Brain (most abundant in hippocampus and amygdala), placenta and lung. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12858959 |
| Subcellular location [CC] | Nucleus speckle {ECO:0000269|PubMed:19136466}. Note=When splicing is inhibited, accumulates in enlarged speckles. |
| Mouse PG classification | LPG |
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