| Gene Information | |
|---|---|
| Gene Name | ARHGAP6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 974 |
| Protein Names | Rho GTPase-activating protein 6 (Rho-type GTPase-activating protein 6) (Rho-type GTPase-activating protein RhoGAPX-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000047648 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | O43182 |
| Gene Card | ARHGAP6 |
| Uniprot ID | O43182 |
| Pfam | PF00620 |
| In ASD | no |
| Allosteric Prediction | no (-0.289887687) |
| Ortholog in Animals | Alpaca_ ARHGAP6 ( ortholog_one2one ) Dog_ ARHGAP6 ( ortholog_one2one ) Macaque_ ARHGAP6 ( ortholog_one2one ) Mouse_ Arhgap6 ( ortholog_one2one ) Rat_ Arhgap6 ( ortholog_one2one ) |
| Ohnologs | ARHGAP36 |
| Paralogs | ARHGAP36 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in kidney, heart and skeletal muscle followed by retina, lymphoblast, placenta, lung, brain, pancreas and liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1009758 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10699171}. |
| Mouse PG classification | NA |
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