| Gene Information | |
|---|---|
| Gene Name | DNALI1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 258 |
| Protein Names | Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000163879 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O14645 |
| Gene Card | DNALI1 |
| Uniprot ID | O14645 |
| Pfam | PF10211 |
| In ASD | no |
| Allosteric Prediction | no (-1.317093127) |
| Ortholog in Animals | Alpaca_ DNALI1 ( ortholog_one2one ) Dog_ DNALI1 ( ortholog_one2one ) GuineaPig_ DNALI1 ( ortholog_one2one ) Macaque_ DNALI1 ( ortholog_one2one ) Mouse_ Dnali1 ( ortholog_one2one ) Pig_ DNALI1 ( ortholog_one2one ) Rat_ Dnali1 ( ortholog_one2one ) Rabbit_ DNALI1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in many tissues. A smaller 0.9 kb and a larger 2.5 kb transcripts were detected at the highest level in the testis, at medium levels in the prostate, heart, liver, lung and pancreas, at low levels in the ovary, skeletal muscle and small intestine. Not detected in spleen, colon epithelium, thymus or peripheral blood leukocytes. The 0.9 kb transcript is expressed at a 20-fold higher level than the 2.5 kb transcript in the testis. Expressed in spermatozoa and airway epithelial cells (at protein level) (PubMed:31178125). {ECO:0000269|PubMed:31178125}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11749 rs1266159589 |
| Subcellular location [CC] | Cell projection, cilium {ECO:0000269|PubMed:27120127}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:31178125}. Dynein axonemal particle {ECO:0000250|UniProtKB:Q6GN86}. Cytoplasm {ECO:0000250|UniProtKB:Q8BVN8}. |
| Mouse PG classification | NA |
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