| Gene Information | |
|---|---|
| Gene Name | KLC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 622 |
| Protein Names | Kinesin light chain 2 (KLC 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000174996 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9H0B6 |
| Gene Card | KLC2 |
| Uniprot ID | Q9H0B6 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.338667709) |
| Ortholog in Animals | Alpaca_ KLC2 ( ortholog_one2one ) GuineaPig_ KLC2 ( ortholog_one2one ) Macaque_ KLC2 ( ortholog_one2one ) Mouse_ Klc2 ( ortholog_one2one ) Pig_ KLC2 ( ortholog_one2one ) Rat_ Klc2 ( ortholog_one2one ) |
| Ohnologs | KLC3, KLC1, KLC4 |
| Paralogs | KLC1, APPBP2, KLC3, NPHP3, KLC4 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3CEQ (X-ray 2.75A ) 3EDT (X-ray 2.70A ) |
| DBSNP | rs2276036 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000305}. Lysosome membrane {ECO:0000269|PubMed:22172677}; Peripheral membrane protein {ECO:0000305|PubMed:22172677}; Cytoplasmic side {ECO:0000305|PubMed:22172677}. |
| Mouse PG classification | NA |
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