| Gene Information | |
|---|---|
| Gene Name | AP3S1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 193 |
| Protein Names | AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Clathrin-associated/assembly/adaptor protein, small 3) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000177879 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q92572 |
| Gene Card | AP3S1 |
| Uniprot ID | Q92572 |
| Pfam | PF01217 |
| In ASD | no |
| Allosteric Prediction | no (-0.8399524) |
| Ortholog in Animals | Alpaca_ AP3S1 ( ortholog_one2one ) Dog_ AP3S1 ( ortholog_one2one ) GuineaPig_ AP3S1 ( ortholog_one2one ) Macaque_ AP3S1 ( ortholog_one2one ) Mouse_ Ap3s1 ( ortholog_one2one ) Rat_ Ap3s1 ( ortholog_one2one ) |
| Ohnologs | AP3S2 |
| Paralogs | AP1S1, AP1S2, AP1S3, AP3S2, AP2S1, AP4S1 |
| Tissue | NA |
| Tissue Specificity | Present in all adult tissues examined. {ECO:0000269|PubMed:8697810, ECO:0000269|PubMed:9118953, ECO:0000269|PubMed:9151686}. |
| Pharmacological Animal Models | 0.037766(Chimpanzee);0.014452(Mouse);0.001899(Rat);0.018182(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7733604 |
| Subcellular location [CC] | Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. |
| Mouse PG classification | NA |
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